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5 Must-Have Lion’s Mane Mushroom Capsules for Sharpening Your Focus

What to look for in 2024’s highly-rated mushroom supplements + how these winning formulas can improve your memory and mood.

  • Written by: Brilliant Staff
  • Fact-checked by: Melissa Mitri, MS, RD
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With jam-packed schedules and never-ending responsibilities, most of us can feel like we’re being pulled in a hundred different directions every day. Unfortunately, this can take a huge toll on our mental health, making it more difficult to focus; leading to burnout.

Enter a potent and effective lion’s mane mushroom supplement. Research has shown it can give your mind – and body – the support it craves.

Key Benefits of Lion’s Mane Mushroom Supplements

Sharpens Focus & Memory

Lion’s mane contains two unique compounds, hericenones and erinacines, which have been shown to enhance mental focus and help improve memory.

A clinical trial in Japan revealed that adults with memory concerns showed significant improvement after ingesting lion’s mane supplement capsules over those who didn’t.

Promotes Positive & Consistent Mood

Lion’s mane mushroom has been cited in clinical studies with demonstrated improvement in mental health scores. Its ability to exert benefits in the brain can encourage a more positive and stable mood.

Fortifies Gut Health

Studies have found that lion’s mane extract may reduce the growth of unwanted bacteria in the gut, which impacts proper digestion. At the same time, lion’s mane stimulates the growth of healthy bacteria, helping to bolster the gut microbiome.
But before you go ahead and press “buy now” on just any lion’s mane mushroom supplement, there are a few things to keep in mind. Not all products are created equal. That’s why we’ve provided a list of some key ingredients to look for, as well as what to avoid.

Step 1

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Step 2

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Step 3

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Key Ingredients in a High-Quality
Lion’s Mane Mushroom Formula

1000 mg lion's mane

You want the formula to include a sufficient amount of lion’s mane mushroom. For best results, we recommend choosing a product with at least 1,000 mg per serving.

Mushroom Blend for extra benefits

There is a growing trend in the health community called “mushroom stacking” which aims to get the most out of functional mushrooms by combining multiple varieties together. Popular ones include lion’s mane, reishi, turkey tail, cordyceps, shiitake, and chaga.

These mushrooms can yield impressive benefits for your mind and body, which includes promoting mental clarity, gut and heart health, and reducing oxidative stress. As long as the formula contains 1,000 mg of lion’s mane, you’ll appreciate the extra ingredients and the healthy incentives they can help deliver for your overall well-being.

Fruiting body for maximum potency

Mushrooms are composed of two primary parts: mycelium and a fruiting body. The mycelium (pl., mycelia), is a network of roots that exist underground. The fruiting body is the more familiar part of the mushroom, and consists of the stalk and cap.

There is a continuing debate among experts over whether mycelium or the fruiting body hold the most benefits. However, most of the research into the benefits of functional mushrooms focuses on the fruiting body, which is why all of the products featured below are formulated with the fruiting body.

Watch Out For

Misleading labels

Some lion’s mane supplements claim to be formulated with high quantities of mushrooms. However, if you examine the label, specifically the extract ratio, it will usually read 4:1 or 10:1. This means 10 grams of raw mushroom material was used to create 1 gram of extract. The finished product is the extract, so it may look like there’s more in the formula than there actually is.

With that in mind, if a supplement claims to contain high amounts of a mushroom extract, such as 10,000 grams, but you see a ratio of 10:1, be aware that only a small amount of extract is in the formula, usually 1 gram. If an extract ratio is not included, or it says 1:1, you know you’re getting the amount the mushroom capsules claim.

Products not third-party tested

When a brand claims to meet specific health and safety requirements, you want to ensure a viable source backs them up. Third-party testing is performed by an independent organization not associated with the company manufacturing the supplement. It’s their job to evaluate the quality, safety, purity, and potency of the product.

Frequently Asked Questions

What are the benefits of lion’s mane?

Lion’s mane supports cognitive, gut, and immune health. It helps the brain by encouraging healthy nerve cells and reinforcing the gut microbiome, which is linked to multiple aspects of mental wellness. Lion’s mane also promotes a stronger immune system by providing naturally occurring beta-glucan fibers.

Is lion’s mane a psychedelic mushroom?

No, lion's mane does not have a hallucinogenic effect on the brain. Unlike psychedelic mushrooms, functional mushrooms can offer extraordinary health benefits without altering the mind. Lion's mane has been extensively studied for its cerebral and sensory development benefits, which can lead to improved memory and a sense of calmness with continuous use.

Are there any side effects of lion’s mane?

There are no serious side effects associated with lion’s mane mushroom supplementation. However, some people may experience mild digestive discomfort when trying new supplements. If you are sensitive, you may want to begin with a smaller dose and gradually increase to the suggested amount. As always, it's important to talk to a healthcare professional before adding a new supplement to your regime.
Now that we’ve covered what to look for and avoid in lion’s mane mushroom supplements, it’s time to shop! Check out our Brilliant recommendations below, including our own Live Conscious® Lion’s Mane + Mushroom Blend.
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2024’s Must-Have Lion’s Mane Supplements

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What is lorum ipsum?

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What is lorum ipsum?

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What We Like:

    • 1,100 mg of lion’s mane
    • Mushroom blend
    • Fruiting bodies
    • Non-GMO
    • Vegan 
    • Third-party tested 
    • Made in USA with local & global ingredients
    • 365-day money-back guarantee

Room To Improve:

    • New to market

Final Thoughts

Live Conscious Lion’s Mane + Mushroom blend contains 1,100 mg of lion’s mane and a 200 mg advanced adaptogen complex of cordyceps, turkey tail, and reishi, specifically formulated to support  focus, memory, gut health, and immune health. 



Our mushrooms are 100% fruiting body mushrooms. They are non-GMO, vegan, and contain no unnecessary fillers or added ingredients.

Product Specs

  • 60 capsules per bottle (30 servings) 
  • Organic lion's mane fruiting body powder (1,100 mg), advanced adaptogen complex – organic cordyceps sinensis, organic cordyceps militaris, organic turkey tail, organic reishi (200 mg)
  • Gluten-free, preservative-free, non-GMO, vegan
  • Price: $$

What We Like:

    • 1,000 mg of lion’s mane
    • Mushroom blend
    • Fruiting bodies
    • Non-GMO 
    • Vegan
    • Third-party tested
    • 90-day money back guarantee
    • Manufactured in the USA with globally-sourced ingredients

Room To Improve:

    • High price point

Final Thoughts

Stonehenge Health Dynamic Mushroom supplement is formulated with 1,000 mg of the fruiting bodies of lion’s mane, chaga, maitake, shiitake, and reishi. The main downside is Stonehenge's formula has the highest price point of all products on this list, but you can utilize their subscribe and save program and save 15%. 

Product Specs

  • 60 capsules per bottle (30 servings) 
  • Lion’s mane (1,000 mg), chaga (100 mg), maitake (100 mg), shiitake (100 mg), reishi (100mg)
  • Gluten-free, soy-free, dairy-free, non-GMO, vegan
  • Price: $$$

*We earn a commission if you click on this link to make a purchase of Stonehenge Health Dynamic Mushrooms

What We Like:

    • 1,000 mg of lion’s mane
    • Fruiting bodies
    • Non-GMO 
    • Vegan 
    • Third-party tested
    • Certified organic

Room To Improve:

    • No mushroom blend
    • Formula potency
    • 30-day return policy

Final Thoughts

Ancient Nutrition Lion’s Mane is USDA-certified organic, made with fruiting body mushrooms as well as mycelium. It contains a blend of lion’s mane mushroom and ashwagandha. Ashwagandha is an excellent ingredient for mental clarity, making it a great fit for this supplement. One downside is the amount of lion’s mane per serving is below our recommended 1,000 mg dose.

Product Specs

  • 30 capsules per bottle (30 servings) 
  • Lion’s mane and ashwagandha (1,000 mg)
  • Gluten-free, non-GMO, vegan, keto friendly, USDA organic
  • Price: $

*We earn a commission if you click on this link to make a purchase of Ancient Nutrition Lion's Mane

What We Like:

    • Mushroom blend
    • Non-GMO 
    • Vegan
    • Third-party tested
    • 180-day return policy
    • Manufactured in the USA with globally-sourced ingredients

Room To Improve:

    • Contains only 266 mg of lion’s mane
    • Formula potency
    • High price point

Final Thoughts

With a diverse formula, including lion’s mane, cordyceps, reishi, shiitake, and 10 other medicinal mushrooms,  Dr. Love targets cognitive health. However, at just 266 mg per serving of lion’s mane, it’s considerably less potent than other products featured on this list. One other downside is its price point at nearly $60 a bottle.

Product Specs

  • 60 capsules per bottle (30 servings)
  • Lion’s mane (266 mg), cordyceps sinensis powder (266 mg), reishi mushroom extract (266 mg), shiitake mushroom extract (266 mg) 
  • Gluten-free, non-GMO, vegan
  • Price: $$$

*We earn a commission if you click on this link to make a purchase of Dr. Love Roar Lion's Mane

What We Like:

    • 1,000 mg Lion’s Mane
    • Fruiting bodies
    • Non-GMO
    • Vegan
    • Made with certified organic mushrooms
    • Third-party tested

Room To Improve:

    • No mushroom blend
    • 30-day return policy

Final Thoughts

Real Mushrooms Lion’s Mane Extract is about as straightforward as you can get. This formula contains the recommended amount of lion’s mane at 1,000 mg per serving. However, it lacks a mushroom blend for additional benefits. At a similar price point to others on our list, this option includes double the number of capsules as other competitors with a 60-day supply.

Product Specs

  • 120 capsules per bottle (60 servings)
  • Lion’s mane (1,000 mg)
  • Gluten-free, non-GMO, vegan
  • Price: $

*We earn a commission if you click on this link to make a purchase of Real Mushroom's Lion's Mane

The Brilliant Process

How We Choose Products

Like you, we’re picky about products — and serious about quality

Whether we’re featuring an award-winning product from one of our five beauty and wellness brands — or somebody else’s — a Brilliant recommendation doesn’t see the light of day until it has been medically reviewed for accuracy and has fulfilled our Brilliant Criteria.

At Brilliant, although we often feature products that we sell, we’re not afraid to highlight and celebrate other brands who are doing things right.

Brilliant Criteria

We take great care in handpicking high-quality products to feature on Brilliant. Here’s how we choose them:
  • High-Quality Ingredients: We dig deep into the latest research and look for products that contain science-based ingredients for optimal impact.
  • Pure, Holistic Formulas: We prioritize products that contain clean, wholesome ingredients shown to be effective. A product should only contain what it needs and nothing else — period.
  • Brand Credibility: Each product on our list is produced by a company with trusted credibility. We've also verified that each brand adheres to labeling requirements set forth under current Good Manufacturing Practices (cGMP).
  • Value: We evaluate products based on industry averages and price per serving or application. We also consider quantity and return policy.

Why Trust Us?

As veteran leaders in the wellness space with an award-winning brand portfolio of 100+ health and beauty products, we are committed to honesty and transparency, providing unbiased insights into the benefits and limitations of the information and products we evaluate — including our own. Every Brilliant Buying Guide is thoroughly vetted for medical accuracy by our Fact Checkers prior to publication.

With our discerning selection process, you can feel confident that the products we recommend meet the highest benchmarks of quality, transparency, and efficacy. If we wouldn’t use a product ourselves, it’s not Brilliant.

Citations

1. Puei-Lene Lai, et al. International Journal of Medicinal Mushrooms, U.S. National Library of Medicine, 2013; 15(6): 539-54, https://doi.org/10.1615/intjmedmushr.v15.i6.30
2. Spelman, Kevin, et al. Journal of Restorative Medicine, vol. 6, no. 1, 1 Dec. 2017, pp. 19–26, https://doi.org/10.14200/jrm.2017.6.0108.
3. Chong, Pit Shan, et al. International Journal of Molecular Sciences, 2020, 21(1), 163, https://doi.org/10.3390/ijms21010163
4. Kushairi, Naufal, et al. Antioxidants, U.S. National Library of Medicine, 2019 Aug; 8(8): 261, https://www.mdpi.com/2076-3921/8/8/261
5. Julson, Erica. Healthline, 19 May 2018, www.healthline.com/nutrition/lions-mane-mushroom. Accessed 20 Nov. 2023. 
6. Bedosky, Lauren, and Justin Laube. EverydayHealth.com, 3 Oct. 2022, www.everydayhealth.com/wellness/lions-mane/guide/.
7. Monagas, Maria, et al. Frontiers in Pharmacology, vol. 13, no. 36249773, 30 Sept. 2022, p. 981978, www.ncbi.nlm.nih.gov/pmc/articles/PMC9561911/, https://doi.org/10.3389/fphar.2022.981978.
8. “Lion’s Mane.” PubMed, National Institute of Diabetes and Digestive and Kidney Diseases, 2012, www.ncbi.nlm.nih.gov/books/NBK599740. Accessed 20 Mar. 2024.
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