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2025’s Top-Rated Menopause & Perimenopause Supplements for Balanced Hormones
The key ingredients every woman should look for in a hormone supplement to ease their most troublesome menopause symptoms.
Written by Brilliant Staff
Fact Checked by Melissa Mitri, MS, RD
Millions of women are dealing with mood swings, hot flashes, weight gain, and sleepless nights—thinking they just have to tough it out. In fact, it’s common for relationships and careers to become strained during this tough transition. It can be truly life-altering. Finding the right support can ease the struggle and transform your experience.
Since everyone’s menopause experience is different, it can be hard to know where to find real answers. While herbs and supplements are great to turn to in your time of need, it’s often overwhelming to try to sift through all the options to figure out what’s right for you.
We’re here to help you zero in on what really works so you can find the menopause supplement that’s a perfect match for your unique needs.
Menopause Symptoms Decoded: What’s Really Happening?
While shifts in estrogen levels are the main culprit behind your menopause symptoms, that doesn’t tell the whole story.
Estrogen plays a role in regulating serotonin and other neurotransmitters, so when it declines, it can impact mood and mental health. If you’ve noticed extra weight gain lately, it’s not your imagination—it’s how declining estrogen and rising cortisol impact your metabolism.
Your body also needs extra support detoxifying and clearing out hormones it no longer needs. Supporting the liver in this important process also benefits estrogen levels and keeps the ratio of androgens, such as testosterone, in a healthy range.
Benefits of an Effective Menopause Supplement
Reduces hot flash severity
Enhances mood
Curbs food cravings
Reduces menopausal weight gain
Supports healthy sex drive
Improves sleep
Reduces brain fog
Decreases fatigue
A well-formulated menopause supplement tackles multiple symptoms at once, thanks to multitasking ingredients that help you take control and feel like yourself again.
Key Multitasking Ingredients
- Stabilizes mood
- Benefits sleep
- Encourages a healthy weight
- Keeps blood sugar balanced
- Supports healthy bone density
- Helps reduce menopause-related belly fat
- Supports estrogen conversion
- Assists weight management
- Reduces sugar cravings
- Helps maintain healthy cholesterol levels
- Eases stress levels
- Benefits mood regulation
- Promotes a healthy heart
- Supports healthy estrogen conversion
- Promotes androgen/estrogen balance
- Reduces hot flashes & night sweats
- Improves hormonal non-cystic acne
- Keeps moods balanced
- Reduces irritability
- Supports estrogen/progesterone balance
- Benefits vaginal dryness
- Promotes quality sleep
- Eases hot flashes
- Keeps libido up
- Uplifts mood & mental health
- Invigorates energy
- Supports memory and focus
- Helps soothe daily stress
Watch Out For
The right ingredients matter, but the right amounts matter even more. Make sure your perimenopause/menopause supplement delivers scientifically-studied dosages to experience the full range of benefits.
Watch out for “proprietary blends” in menopause supplements, which keep ingredient amounts a mystery. A quality product has nothing to hide. Look for a supplement company that tells you exactly how much is in every dose, so you can be sure you are getting enough to feel the effects.
Effective menopause supplements won’t be packed with useless fillers and unnecessary additives. Avoid questionable ingredients and look for clean supplements that are designed for real results.
Quality matters. Third-party testing guarantees your supplement meets strict safety standards, so you can trust that what you’re taking is free from metals, contaminants, and anything you don’t want in your body.
More to Think About
There are many different kinds of supplements that contribute to a healthy menopause journey, so it might be confusing to know where to begin.
Many menopause supplements only address a few symptoms, but don’t tackle the underlying causes. Menopause is very complex and you need a supplement that works with your body to restore balance—not just mask symptoms. Quick fixes, single-ingredient products, or weak formulations often leave gaps in support and won’t give you lasting results.
You’ll notice premium menopause supplements come with a higher price tag, but this isn’t the time or place to cut corners. Investing in your health and comfort during this transition is a decision you’ll never regret. Choosing a trusted brand with a reliable money-back guarantee will give you peace of mind and added confidence in your purchase.
Now that you know what to look for and avoid in menopause supplements, it’s time to shop. Check out our Brilliant recommendations below, including our own Live Conscious® Beyond Hormone™.
*Per 2 gram serving size
2025’s Must-Have Hormone Health Supplements
What We Like:
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Myo-inositol
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D-chiro-inositol
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Berberine
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DIM (diindolylmethane)
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Chaste tree berry
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Gluten free
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Non-GMO
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Third-party tested
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365-day money-back guarantee
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Manufactured in the USA with global ingredients
Room To Improve:
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Not always in stock
Not always in stock
Final Thoughts
Our comprehensive formula emphasizes efficacy to ensure extra support for menopausal symptoms. It was developed with meaningful ingredients at meaningful doses, to target and help reduce hot flashes, mood swings, food cravings, and bloating reduction, plus consistent weight management and a healthy sex drive.
Product Specs
- 90 capsules per bottle (30 servings)
- Myo-inositol (1500 mg), d-chiro-inositol (37.5 mg), berberine HCI bark extract (500 mg), chaste tree berry extract (30 mg), maca root extract (36 mg), DIM (75 mg), vitamin B6 (3.4 mg), folate (as folic acid 240 mcg)
- Gluten-free, soy-free, dairy-free, non-GMO
- Price: $$$
What We Like:
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Berberine
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Chaste tree berry
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Gluten free
-
Non-GMO
-
Third-party tested
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60-day return policy
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Manufactured in the USA with local & global ingredients
Room To Improve:
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Proprietary blend
Final Thoughts
Happy Mammoth’s Hormone Harmony™ is formulated with berberine, chaste tree berry, and maca root. It also contains rhodiola and ashwagandha extracts to help ease stress and support healthy cortisol levels. Even though it’s on the pricier side, Happy Mammoth®provides a robust 60-day return policy. However, this supplement incorporates a proprietary blend, so unfortunately you can’t be certain of the specific dosage of each ingredient and if it will ultimately be effective.
Product Specs
- 72 capsules per bottle (24 servings)
- HM5 MenoBalance Complex™ (1135 mg), HM4 MenoShred Complex™ (642 mg), HM3 MenoMood Complex™ (300 mg)
- Gluten-free, soy-free, vegan, non-GMO
- Price: $$$
What We Like:
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Gummy or capsule option
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Chaste tree berry
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Gluten free
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Non-GMO
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Third-party tested
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60-day return policy
Room To Improve:
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Color Additives
Final Thoughts
O-Positiv’s Meno® stands out with a well-crafted formula in the menopause supplement space. It features ingredients that may help reduce symptoms, especially chaste tree berry and ashwagandha. In addition to missing some key ingredients, like Berberine, another downside of this product is that it contains color additives, including titanium dioxide.
Product Specs
- 60 capsules / bottle (30 servings)
- Vitamin B6 (2 mg), vitamin D3 (15 mcg), ashwagandha KSM 66 (300 mg), chaste berry (40 mg), black cohosh (40 mg)
- Gluten-free, vegan, non-GMO
- Price: $
What We Like:
-
Myo-inositol
-
DIM (diindolylmethane)
-
Gluten free
-
Third party tested
Room To Improve:
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30-day return policy
Final Thoughts
Unlike the other products on this list, Alani Nu’s Balance features l-glutathione, which helps support skin complexion by aiding in hydration. It also includes chromium for blood sugar management and ALA, which pairs well with myo-inositol to support normal insulin sensitivity. We’re not thrilled with their 30-day return policy since it can take up to several months for a supplement to yield results, and we’re hesitant about the product’s credibility because of their big influencer push. Just another trend or does the product actually work?
Product Specs
- 120 capsules / bottle (30 servings)
- Myo-inositol (2g), diindolylmethane (DIM) (150 mg), folate (400 mcg DFE), chromium (120 mcg), setria l-glutathione (250 mg), sodium r-alpha lipoic acid (ALA) (100 mg)
- Gluten-free, vegan, soy-free, dairy-free
- Price: $$
*We earn a commission if you click on this link to make a purchase of Alani Nu®’s Balance
What We Like:
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Chaste tree berry
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Gluten free
-
Non-GMO
-
Third-party tested
-
Manufactured in the USA with global ingredients
Room To Improve:
-
30-day return policy
Final Thoughts
While HUM® doesn’t feature either inositol in its Hormone Balance formula, it does provide chaste tree berry – an ingredient that helps reduce menopausal symptoms. This no-fuss formula is sure to deliver on quality, although we wish they offered more than a 30-day return policy as well as additional hormone balancing ingredients to ease all of your symptoms.
Product Specs
- 60 capsules per bottle (30 servings)
- Chaste tree berry extract (600 mg), dong quai root powder (300 mg)
- Vegan, non-GMO, dairy-free, soy-free
- Price: $
Frequently Asked Questions
Powerful menopause supplements, along with a healthy diet and lifestyle, can help reduce hot flashes, mood swings, food cravings, weight gain, lack of sex drive, and other uncomfortable symptoms. Potent, naturally occurring ingredients like chaste tree berry, berberine, and maca root in an effective formula can promote a more positive mood and body temperature, better sleep, and less cramping.
A scientifically formulated product will balance hormones, improve metabolic and ovarian health, help reduce bloating, support mental clarity, positive mood, consistent energy levels, weight management, and a healthy sex drive.
Certain products will include berberine, a key ingredient that promotes healthy weight management. The formula may also feature vitamin B6 and maca root, which can aid digestion and help reduce bloating.
The Brilliant Process
Like you, we’re picky about products — and serious about quality.
Whether we’re featuring an award-winning product from one of our five beauty and wellness brands — or somebody else’s — a Brilliant recommendation doesn’t see the light of day until it has been medically reviewed by our Fact Checkers for accuracy and has fulfilled our Brilliant Criteria.
At Brilliant, although we often feature products that we sell, we’re not afraid to highlight and celebrate other brands who are doing things right.
We take great care in handpicking high-quality products to feature on Brilliant. Here’s how we choose them:
- High-Quality Ingredients: We dig deep into the latest research and look for products that contain comprehensive ingredients for optimal impact.
- Pure, Holistic Formulas: We prioritize products that contain clean, wholesome ingredients. A product should only contain what it needs and nothing else—period.
- Brand credibility: Each product on our list is produced by a company with trusted credibility. We've also verified that each brand adheres to labeling requirements set forth under current Good Manufacturing Practices (cGMP).
- Value: We evaluate products based on industry averages and price per serving or application. We also consider quantity and return policy.
As veteran leaders in the wellness space with an award-winning brand portfolio of 100+ health and beauty products, we are committed to honesty and transparency, providing thoughtful insights into the benefits and limitations of the information and products we evaluate — including our own. Every Brilliant Buying Guide is thoroughly vetted for medical accuracy by our Fact Checkers prior to publication.
With our discerning selection process, you can feel confident that the products we recommend meet the highest benchmarks of quality, transparency, and efficacy. If we wouldn’t use a product ourselves, it’s not Brilliant.
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